Section Gene Symbol Age Orientation Objective Veracity Veracity Support 09 paired box gene 6 Pax6 P7 Sagittal 10X Confirmed Multiple Lines Match Matches In Situ Data Supported by Literature

BX BAC Address marker BX456 RP23-431C3 EGFP

Other cross-sections of this brain: 01 02 03 04 05 06 07 08 09 10 11 (thumbnails not to scale)

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Add this image to your album Download this image at the scale shown below. Founder Line: BV100 See all MMRRC strains for : Pax6 Get this mouse from MMRRC: STOCK Tg(Pax6-EGFP)BV100Gsat/Mmnc: Details, Order Get this BAC Clone from CHORI: BX456 UCSC Genome Browser for this BAC Address: RP23-431C3

Read gene expression annotations for this image View other image sets for Pax6

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Comment on this Gene: Two BAC lines have matching expression at P7. Our BAC data grossly matches the literature and the in situ data from BGEM and Genepaint.org. But there are a few discrepancies: 1. Scattered glial cells are reproducibly stained in the hindbrain in two different targeting events. 2. Little or no expression in hippocampus in BAC mice at P7 and E15-5, compared with the in situ data.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Olfactory Bulb	moderate to strong signal	region-specific and scattered	neuron glial cell other	granule cell of MOB mitral cell of MOB other
Cerebral cortex	moderate to strong signal	widely expressed	neuron glial cell
Anterior Olfactory Nucleus	moderate to strong signal	region-specific and scattered	glial cell other not clear
Hippocampus	weak signal	scattered	glial cell
Septum	moderate to strong signal	scattered	neuron glial cell
Ventral striatum	moderate to strong signal	region-specific and scattered	neuron glial cell	fibers
Basal Forebrain	moderate to strong signal	scattered	neuron	fibers
Thalamus	moderate to strong signal	region-specific and scattered	neuron	fibers
Hypothalamus	moderate to strong signal	scattered		fibers
Midbrain	moderate to strong signal	region-specific and scattered		fibers
Pons	moderate to strong signal	scattered	glial cell
Medulla	moderate to strong signal	scattered	glial cell
Cerebellum	moderate to strong signal	region-specific	neuron	granule neuron of cerebellum fibers
other: Rostral migratory stream	moderate to strong signal	widely expressed	other
Corpus callosum	moderate to strong signal	ND
Fornix	moderate to strong signal	ND

Other image sets for Pax6

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	BV100	3 images
adult	Horizontal	confocal	BV100	1 images
adult	Sagittal	brightfield	BV100	10 images
adult	Sagittal	confocal	BV100	1 images
adult	Sagittal	confocal	BV100	8 images
P7	Horizontal	brightfield	BV100	3 images
P7	Horizontal	confocal	BV100	2 images
P7	Sagittal	brightfield	BV100	11 images
P7	Sagittal	confocal	BV98	2 images
P7	Sagittal	confocal	BV100	1 images
P7	Sagittal	confocal	BV100	12 images
E15.5	Horizontal	brightfield	BV98	3 images
E15.5	Sagittal	brightfield	BV98	10 images

BGEM Probe	Related ISH images
Pax6	294

Supporting literature:

PubMed ID
9108373
11050125
8126546
11688562

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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