Section Gene Symbol Age Orientation Objective Veracity Veracity Support 10 WW, C2 and coiled-coil domain containing 1 Wwc1 E15.5 Sagittal 10X Confirmed Multiple Lines Match Matches In Situ Data Supported by Literature

BX BAC Address marker BX2516 RP23-442N12 EGFP

Other cross-sections of this brain: 01 02 03 04 05 06 07 08 09 10 (thumbnails not to scale)

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Add this image to your album Download this image at the scale shown below. Founder Line: OJ47 See all MMRRC strains for : Wwc1 Get this mouse from MMRRC: STOCK Tg(Wwc1-EGFP)OJ47Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX2516 UCSC Genome Browser for this BAC Address: RP23-442N12

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Comment on this Gene: Limited CNS expression literature. The BAC data is reproducible and consistent with the literature and the in situ data from Allen database. The BAC is mainly expressed in the cortex and hippocampus. EGFP expression is also present in the hypothalamus, cerebellum and medial habenular nucleus.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Cerebral cortex	moderate to strong signal	region-specific
Septum	moderate to strong signal	region-specific
Basal Forebrain	moderate to strong signal	region-specific
Thalamus	undetectable	ND
Hypothalamus	weak signal	region-specific
Midbrain	weak signal	region-specific
Pons+Medulla	weak signal	region-specific
Cerebellum	weak signal	region-specific

Other image sets for Wwc1

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	OJ47	3 images
adult	Sagittal	brightfield	OJ47	10 images
E15.5	Horizontal	brightfield	OJ47	2 images
E15.5	Sagittal	brightfield	OJ47	10 images

BGEM Probe	Related ISH images
Wwc1	3792

Supporting literature:

PubMed ID
18672031
18789830

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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