Section Gene Symbol Age Orientation Objective Veracity Veracity Support 05 cystatin C Cst3 P7 Sagittal 10X Confirmed Matches In Situ Data Supported by Literature

BX BAC Address marker BX2542 RP23-389I20 EGFP

Other cross-sections of this brain: 01 02 03 04 05 06 07 08 09 10 11 (thumbnails not to scale)

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Add this image to your album Download this image at the scale shown below. Founder Line: PE159 See all MMRRC strains for : Cst3 Get this mouse from MMRRC: STOCK Tg(Cst3-EGFP)PE159Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX2542 UCSC Genome Browser for this BAC Address: RP23-389I20

Read gene expression annotations for this image View other image sets for Cst3

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Comment on this Gene: No detailed expression literature found. The two cited papers don_t correlate well. One paper reports that Cst3 is expressed in cortical neurons of layer 3 and 5 in human, which seems to be confirmed by BGEM P7 in situ data. The other paper reports the gene is expressed in astrocytes, which is supported by the in situ data from Allen database. The BAC data is consistent with Allen in situ data. EGFP expression is mostly present in glial cells across the CNS.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Cerebral cortex	moderate to strong signal	region-specific and scattered	neuron glial cell
Piriform cortex	moderate to strong signal	scattered	glial cell
Hippocampus	moderate to strong signal	region-specific and scattered	neuron glial cell
Caudate Putamen	moderate to strong signal	scattered	glial cell
Ventral striatum	moderate to strong signal	scattered	glial cell
Globus Pallidus	moderate to strong signal	scattered	glial cell
Basal Forebrain	moderate to strong signal	scattered	glial cell
Amygdala	moderate to strong signal	scattered	glial cell
Thalamus	moderate to strong signal	scattered	glial cell
Midbrain	moderate to strong signal	scattered	glial cell
Pons	moderate to strong signal	scattered	glial cell
Medulla	moderate to strong signal	scattered	glial cell
Cerebellum	moderate to strong signal	region-specific and scattered	glial cell

Other image sets for Cst3

age	orientation	Acquisition technique	Founder Line	Batch
P7	Horizontal	brightfield	PE159	3 images
P7	Sagittal	brightfield	PE159	11 images

BGEM Probe	Related ISH images
Cst3	1302

Supporting literature:

PubMed ID
11549598
15509901

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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