GENSAT Project at Rockefeller University, Mouse Brain Atlas, Image Navigator

Section	Gene	Symbol	Age	Orientation	Objective	Veracity	Veracity Support
03	sine oculis-related homeobox 3	Six3	adult	Sagittal	10X	Confirmed	Matches In Situ Data Supported by Literature

BX	BAC Address	marker
BX2506	RP24-68F22	EGFP

Other cross-sections of this brain:

GENSAT Brain Atlas, expression of gene Six3 in mouse age adult, brightfield image

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Founder Line: OF35

See all MMRRC strains for : Six3

Get this mouse from MMRRC: STOCK Tg(Six3-EGFP)OF35Gsat/Mmucd: Details, Order

Get this BAC Clone from CHORI: BX2506

UCSC Genome Browser for this BAC Address: RP24-68F22

View other image sets for Six3

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Comment on this Gene:
The BAC data is very incomplete. Correct expression is observed in the optic tract, retina and hypothalamus. However, the BAC misses important expression sites, such as the reticular thalamic nucleus and inferior colliculus. In the reticular thalamic nucleus, scattered glial cells are stained in BAC data. The BGEM in situ data also show weak Six3 expression in the striatum and SNR, which is absent in the BAC data.

Other image sets for Six3

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	OF35	2 images
adult	Sagittal	brightfield	OF35	10 images
P7	Horizontal	brightfield	OF35	3 images
P7	Sagittal	brightfield	OF35	11 images

BGEM Probe	Related ISH images
Six3	1136

Supporting literature:

PubMed ID
8575305
14522868

Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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