Section Gene Symbol Age Orientation Objective Veracity Veracity Support 11 notch 1 Notch1 P7 Sagittal 10X Confirmed Multiple Lines Match Matches In Situ Data Supported by Literature

BX BAC Address marker BX2433 RP23-448D8 EGFP

Other cross-sections of this brain: 01 02 03 04 05 06 07 08 09 10 11 (thumbnails not to scale)

Double-click anywhere in the image below. Trouble? Visit help page.

Add this image to your album Download this image at the scale shown below. Founder Line: NH68 Get this BAC Clone from CHORI: BX2433 UCSC Genome Browser for this BAC Address: RP23-448D8

Read gene expression annotations for this image View other image sets for Notch1

Detail Scale: 1:1 1:2 1:4 1:8 Cosmetic edits were introduced to improve the presentation of this image (for example to repair rips, tears, and bubbles). To view edits, click here.

Instructions Click once, somewhere in the image. A new window will pop up displaying selected detail. There is no need to double click. If you change detail scale, new detail will load automatically.

Comment on this Gene: Multiple BAC lines have identical expression at P7. The BAC data is consistent with both the literature and BGEM in situ data. By EGFP epifluorescence, high levels of expression are present in the SVZ, RMS, DG and cerebellum. Within the cerebellum, most of EGFP expressing cells are located near the Purkinje cell layer. They appears to be Bergmann glia and Purkinje neurons. At E15-5, the BAC is strongly expressed in the VZ.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Olfactory Bulb	moderate to strong signal	region-specific and scattered	neuron glial cell vascular cell
Cerebral cortex	moderate to strong signal	widely expressed	glial cell vascular cell
Septum	moderate to strong signal	widely expressed	glial cell vascular cell
Ventral striatum	moderate to strong signal	ND	glial cell vascular cell
Basal Forebrain	moderate to strong signal	widely expressed	glial cell vascular cell
Thalamus	moderate to strong signal	widely expressed	glial cell vascular cell
Hypothalamus	moderate to strong signal	widely expressed	glial cell vascular cell
Midbrain	moderate to strong signal	widely expressed	glial cell vascular cell
Pons	moderate to strong signal	widely expressed	glial cell vascular cell
Medulla	moderate to strong signal	widely expressed	glial cell vascular cell
Cerebellum	moderate to strong signal	region-specific and scattered	glial cell

Other image sets for Notch1

age	orientation	Acquisition technique	Founder Line	Batch

BGEM Probe	Related ISH images
Notch1	2919

Supporting literature:

PubMed ID
15198674
12175503
11807030

---

Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

Top

00:00:01.443