Section Gene Symbol Age Orientation Objective Veracity Veracity Support 10 fibroblast growth factor receptor 3 Fgfr3 adult Sagittal 10X Confirmed Matches In Situ Data

BX BAC Address marker BX1978 RP23-316E8 EGFP

Other cross-sections of this brain: 01 02 03 04 05 06 07 08 09 10 (thumbnails not to scale)

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Add this image to your album Download this image at the scale shown below. Founder Line: KB81 See all MMRRC strains for : Fgfr3 Get this mouse from MMRRC: STOCK Tg(Fgfr3-EGFP)KB81Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX1978 UCSC Genome Browser for this BAC Address: RP23-316E8

Read gene expression annotations for this image View other image sets for Fgfr3

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Comment on this Gene: The E15-5 BAC data matches the literature and the embryonic in situ data from Genepaint.org. In the developing cortex, the EGFP reporter gene is expressed in a rostral-low caudal-high gradient, which is confirmed by the cited paper. Outside the nervous system, the BAC is correctly expressed in the cartilage. The postnatal BAC data needs confirmation. The in situ data from Allen database is not informative.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Olfactory Bulb	moderate to strong signal	scattered	glial cell
Cerebral cortex	moderate to strong signal	scattered	glial cell
Ventral striatum	moderate to strong signal	scattered	glial cell
Basal Forebrain	moderate to strong signal	scattered	glial cell
Thalamus	moderate to strong signal	scattered	glial cell
Hypothalamus	moderate to strong signal	scattered	glial cell
Midbrain	moderate to strong signal	scattered	glial cell
Pons	moderate to strong signal	scattered	glial cell
Medulla	moderate to strong signal	scattered	glial cell
Cerebellum	moderate to strong signal	region-specific and scattered	glial cell

Other image sets for Fgfr3

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	KB81	3 images
adult	Sagittal	brightfield	KB81	10 images
P7	Horizontal	brightfield	KB81	3 images
P7	Sagittal	brightfield	KB81	11 images
E15.5	Horizontal	brightfield	KB81	3 images
E15.5	Sagittal	brightfield	KB81	10 images

BGEM Probe	Related ISH images
Fgfr3	1963

Supporting literature:

PubMed ID
8432397
9050787
11444149
15708559
17181553
15830353

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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