Structure Gene Symbol Age Orientation Objective Veracity Veracity Support Ventral Horn gap junction protein, alpha 1 Gja1 E15.5 Horizontal 25X Confirmed Matches In Situ Data Supported by Literature

BX BAC Address marker BX1977 RP24-289B3 EGFP

Other structures in this brain: OTH SPV

Add this image to your album Download this image at the scale shown below. Founder Line: KB40 See all MMRRC strains for : Gja1 Get this mouse from MMRRC: STOCK Tg(Gja1-EGFP)KB40Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX1977 UCSC Genome Browser for this BAC Address: RP24-289B3

Read gene expression annotations for this image View other image sets for Gja1

Gja1 is expressed in cells in the ventral horn of the developing mouse spinal cord.

Comment on this Gene: The P7 BAC data is consistent with both the literature and BGEM in situ data. The EGFP reporter gene expression can be detected in both neurons and glia. At E15-5, the BAC data overlaps with the in situ data from Genepaint.org. In the developing cortex, the postmitotic cells are stained due to the stability of EGFP protein. However, at adult, the level of EGFP expression is significantly decreased. The adult BAC data is not consistent with the in situ data.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Ventral Horn	moderate to strong signal	region-specific and scattered

Other image sets for Gja1

age	orientation	Acquisition technique	Founder Line	Batch
P7	Horizontal	brightfield	KB40	3 images
P7	Horizontal	confocal	KB40	1 images
P7	Sagittal	brightfield	KB40	11 images
P7	Sagittal	confocal	KB40	7 images
E15.5	Horizontal	brightfield	KB40	2 images
E15.5	Horizontal	confocal	KB40	2 images
E15.5	Sagittal	brightfield	KB40	10 images
E15.5	Sagittal	confocal	KB40	6 images

BGEM Probe	Related ISH images
Gja1	3252

Supporting literature:

PubMed ID
7555741
1337483
9062798

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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