Section Gene Symbol Age Orientation Objective Veracity Veracity Support 10 vasoactive intestinal polypeptide Vip E15.5 Sagittal 10X Confirmed Multiple Lines Match Matches In Situ Data Supported by Literature

BX BAC Address marker BX1866 RP23-25A8 EGFP

Other cross-sections of this brain: 01 02 03 04 05 06 07 08 09 10 (thumbnails not to scale)

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Add this image to your album Download this image at the scale shown below. Founder Line: JN37 See all MMRRC strains for : Vip Get this mouse from MMRRC: STOCK Tg(Vip-EGFP)JN37Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX1866 UCSC Genome Browser for this BAC Address: RP23-25A8

Read gene expression annotations for this image View other image sets for Vip

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Comment on this Gene: The BAC data is reproducible in two different targeting events. The BAC data is consistent with the literature in expression of suprachiasmatic nucleus, superior colliculus and restricted nuclei in the thalamus. In the cortex, scattered cells are labeled that is confirmed by Allen in situ data. The positive cells are not as abundant as the literature indicates. Additional but reproducible expression sites are detected in BAC mice. These sites include motor nuclei in brainstem, amygdala and cerebellum. The E15-5 BAC data grossly matches the in situ data from Genepaint.org.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Olfactory Bulb	undetectable	ND
Cerebral cortex	undetectable	ND
Septum	undetectable	ND
Basal Forebrain	undetectable	ND
Thalamus	undetectable	ND
Hypothalamus	undetectable	ND
Midbrain	weak signal	region-specific
Pons+Medulla	moderate to strong signal	region-specific
Cerebellum	undetectable	ND

Other image sets for Vip

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	JN37	3 images
adult	Sagittal	brightfield	JN37	10 images
adult	Sagittal	confocal	JN37	5 images
P7	Horizontal	confocal	JN37	1 images
P7	Sagittal	brightfield	JN37	11 images
P7	Sagittal	confocal	JN37	6 images
E15.5	Horizontal	brightfield	JN37	3 images
E15.5	Sagittal	brightfield	JN37	10 images
E15.5	Sagittal	confocal	JN37	1 images

BGEM Probe	Related ISH images
Vip	2233

Supporting literature:

PubMed ID
8957535
1436503
2701804

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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