Section Gene Symbol Age Orientation Objective Veracity Veracity Support
T solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 Slc6a4 E15.5 Horizontal 10X Confirmed
  • Multiple Lines Match
  • Matches In Situ Data
  • Supported by Literature
    		•
    BX BAC Address marker
    BX86 RP23-39F11 EGFP
    Other cross-sections of this brain:GENSAT Brain Atlas, expression of gene Slc6a4 in mouse age E15.5, brightfield image
    C    		GENSAT Brain Atlas, expression of gene Slc6a4 in mouse age E15.5, brightfield image
    L    		GENSAT Brain Atlas, expression of gene Slc6a4 in mouse age E15.5, brightfield image
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  • Founder Line: JP55
  • See all MMRRC strains for : Slc6a4
  • Get this mouse from MMRRC: STOCK Tg(Slc6a4-EGFP)JP55Gsat/Mmucd: Details, Order
  • Get this BAC Clone from CHORI: BX86
  • UCSC Genome Browser for this BAC Address: RP23-39F11
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    Comment on this Gene:
    According to the literature, serotonin transporter mRNA is primarily localized in raphe nuclei. The BAC data has correct expression in raphe nuclei. Fiber projection are stained across the CNS, giving an impression that EGFP reporter gene is widely expressed inside. In fact, labeled cell bodies are only observed in a few brain areas at P7, including raphe nuclei. Expression is also observed in the MOB, the thalamus and the cortex. These expression sites are transient during the development and are confirmed by Lebrand C et al paper and BGEM in situ data.

    Gene Expression Annotations for this image
    structureExpression LevelExpression PatternCell typesSubtypes
    Dorsal Hornweak signalscattered
    Ventral Hornmoderate to strong signalscattered
    Dorsal root gangliaundetectableND
    Lateral funiculusmoderate to strong signalND
    Ventral funiculusmoderate to strong signalND


    Other image sets for Slc6a4
    age orientation Acquisition technique Founder Line Batch
    adult Coronal brightfield ET127 16 images
    adult Coronal brightfield ET33 24 images
    adult Coronal brightfield EZ13 69 images
    adult Coronal brightfield EZ8 67 images
    adult Horizontal brightfield JP55 3 images
    adult Sagittal brightfield JP55 10 images
    P7 Horizontal brightfield JP55 3 images
    P7 Sagittal brightfield JP55 11 images
    E15.5 Horizontal brightfield JP55 3 images
    E15.5 Sagittal brightfield JP55 10 images

    BGEM Probe Related ISH images
    Slc6a4 373

    Supporting literature:
    PubMed ID
    9459551
    8121638
    9037532
    9826275


    Veracity definition
    Confirmed Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
    To Be Confirmed To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
    Anomalous Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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