Structure Gene Symbol Age Orientation Objective Veracity Veracity Support Cerebellum neurogenic differentiation 1 Neurod1 E15.5 Sagittal 63X Confirmed Multiple Lines Match Supported by Literature

BX BAC Address marker BX590 RP24-151C22 EGFP

Other structures in this brain: CER2 CER3 CEX2 OEP1 OEP2 OEP3 OTH1 OTH2 PIT TGG

Add this image to your album Download this image at the scale shown below. Founder Line: CR99 See all MMRRC strains for : Neurod1 Get this mouse from MMRRC: STOCK Tg(Neurod1-EGFP)CR99Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX590 UCSC Genome Browser for this BAC Address: RP24-151C22

Read gene expression annotations for this image View other image sets for Neurod1

High magnification image of Neurod1-expressing cells in the developing cerebellum. Compare this confocal photo with brightfield section 5.

Comment on this Gene: Two BAC lines are very similar at P7. Our BAC data is in good agreement with the literature. At P7, highest levels of expression are seen in MOB (glomerular layer), dentate gyrus of the hippocampus and cerebellum (granule cells). Staining is also present in cortex, thalamus, amygdala, colliculi and spinal cord, which have been reported by some of the literature. In the adult BAC brain, levels of EGFP expression in cortex, hippocampus and MOB are greatly reduced. The strong expression remains in cerebellum.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Cerebellum	moderate to strong signal	scattered

Other image sets for Neurod1

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	CR99	3 images
adult	Sagittal	brightfield	CR99	10 images
adult	Sagittal	confocal	CR99	2 images
P7	Horizontal	brightfield	CR99	3 images
P7	Sagittal	brightfield	CR99	11 images
P7	Sagittal	confocal	CR99	4 images
P7	Sagittal	confocal	CR99	1 images
E15.5	Horizontal	brightfield	CR99	3 images
E15.5	Sagittal	brightfield	CR99	10 images
E15.5	Sagittal	confocal	CR99	10 images
E15.5	Sagittal	confocal	CR99	2 images

BGEM Probe	Related ISH images
Neurod1	1224

Supporting literature:

PubMed ID
9454850
10398678
10767080
9039799

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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