Section Gene Symbol Age Orientation Objective Veracity Veracity Support L torsin family 1, member B Tor1b P7 Horizontal 10X Confirmed Multiple Lines Match Supported by Literature

BX BAC Address marker BX1707 RP23-231M11 EGFP

Other cross-sections of this brain: C L T (thumbnails not to scale)

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Add this image to your album Download this image at the scale shown below. Founder Line: IK176 See all MMRRC strains for : Tor1b Get this mouse from MMRRC: STOCK Tg(Tor1b-EGFP)IK176Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX1707 UCSC Genome Browser for this BAC Address: RP23-231M11

Read gene expression annotations for this image View other image sets for Tor1b

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Comment on this Gene: Tor1b is closely related to Tor1a, whose mutation is associated with early onset-dystonia. No detailed CNS expression literature found. Two BAC lines have similar expression at P7. The P7 BAC data is consistent with BGEM in situ data. At adult, the EGFP expression levels decline in most of expression sites except the dentate gyrus. In the adult cerebellum, labeled cells are found mostly in the ML whereas the in situ data shows Tor1b mRNA in the IGL.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Dorsal Horn	moderate to strong signal	region-specific and scattered	neuron
Ventral Horn	moderate to strong signal	scattered	neuron

Other image sets for Tor1b

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	IK176	3 images
adult	Sagittal	brightfield	IK176	10 images
adult	Sagittal	confocal	IK176	9 images
P7	Horizontal	brightfield	IK176	3 images
P7	Sagittal	brightfield	IK176	11 images
P7	Sagittal	confocal	IK176	8 images
P7	Sagittal	confocal	IK176	3 images
E15.5	Horizontal	brightfield	IK176	3 images
E15.5	Horizontal	confocal	IK176	3 images
E15.5	Sagittal	brightfield	IK176	10 images
E15.5	Sagittal	confocal	IK176	6 images

BGEM Probe	Related ISH images
Tor1b	4380

Supporting literature:

PubMed ID
16458269
16938275
11730696

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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