Structure Gene Symbol Age Orientation Objective Veracity Veracity Support
Cerebellum asp (abnormal spindle)-like, microcephaly associated (Drosophila) Aspm P7 Sagittal 25X Confirmed
  • Multiple Lines Match
  • Matches In Situ Data
    		•
    BX BAC Address marker
    BX1643 RP24-267F8 EGFP
    Other structures in this brain:GENSAT Brain Atlas, expression of gene Aspm in mouse age P7, confocal image
    CER    		GENSAT Brain Atlas, expression of gene Aspm in mouse age P7, confocal image
    CEX    		GENSAT Brain Atlas, expression of gene Aspm in mouse age P7, confocal image
    OTH
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  • Founder Line: IH113
  • See all MMRRC strains for : Aspm
  • Get this mouse from MMRRC: STOCK Tg(Aspm-EGFP)IH113Gsat/Mmucd: Details, Order
  • Get this BAC Clone from CHORI: BX1643
  • UCSC Genome Browser for this BAC Address: RP24-267F8
    		•
  • Read gene expression annotations for this image
  • View other image sets for Aspm
    • GENSAT Mouse Brain Atlas, expression of gene Aspm in the Cerebellum of P7 mouse.
    Comment on this Gene:
    Mutation in Aspm gene is associated with primary microcephaly. Aspm protein is localized in mitotic spindle in progenitor cells. The BAC data is reproducible and consistent with BGEM in situ with highest levels of expression in cerebellar EGL, RMS and cells in subventricular zone at P7. The cerebellar IGL is also stained due to the stability of EGFP protein. At adult, EGFP transgene expression remains in RMS and SVZ. At E15-5, the BAC expresses in cells in the ventricular zone. However, the postmitotic cells are labeled due to the stability of EGFP protein.

    Gene Expression Annotations for this image
    structureExpression LevelExpression PatternCell typesSubtypes
    Cerebellummoderate to strong signalregion-specific
  • neuron
  • granule neuron of cerebellum


    • Other image sets for Aspm
    age orientation Acquisition technique Founder Line Batch
    adult Horizontal brightfield IH113 3 images
    adult Sagittal brightfield IH113 10 images
    P7 Horizontal brightfield IH113 3 images
    P7 Sagittal brightfield IH113 11 images
    P7 Sagittal confocal IH113 3 images
    E15.5 Horizontal brightfield IH113 3 images
    E15.5 Horizontal confocal IH113 1 images
    E15.5 Sagittal brightfield IH113 10 images
    E15.5 Sagittal confocal IH113 4 images
    E15.5 Sagittal confocal IH113 4 images

    BGEM Probe Related ISH images
    Aspm 2336

    Supporting literature:
    PubMed ID
    12355089
    16798874
    12351193
    15972725


    Veracity definition
    Confirmed Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
    To Be Confirmed To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
    Anomalous Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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