Structure Gene Symbol Age Orientation Objective Veracity Veracity Support Cerebral cortex crystallin, mu Crym E15.5 Sagittal 40X Confirmed Multiple Lines Match Matches In Situ Data

BX BAC Address marker BX1076 RP24-62I5 EGFP

Other structures in this brain: CEX

Add this image to your album Download this image at the scale shown below. Founder Line: GF82 See all MMRRC strains for : Crym Get this mouse from MMRRC: STOCK Tg(Crym-EGFP)GF82Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX1076 UCSC Genome Browser for this BAC Address: RP24-62I5

Read gene expression annotations for this image View other image sets for Crym

Mu crystallin is expressed in cells in the developing cerebral cortex. Compare this confocal image with brightfield section 5.

Comment on this Gene: Very limited expression literature. The gene is restricted to the dorsal and temporal side of retina. The BAC data is reproducible and is consistent with the in situ data from St Jude and Allen database. Few cells in the layer 6 of the cortex seem to be labeled in the BAC DAB images, but confocal images indicates many pyramidal neurons in that layer are EGFP positive, which agrees with the in situ data. St Jude data reveals strong expression of Crym mRNA in caudate putamen. The BAC expresses in caudate putamen, but at much lower levels.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Cerebral cortex	moderate to strong signal	region-specific

Other image sets for Crym

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	GF82	3 images
adult	Horizontal	confocal	GF82	1 images
adult	Sagittal	brightfield	GF82	10 images
adult	Sagittal	confocal	GF82	6 images
adult	Sagittal	confocal	GF82	8 images
P7	Horizontal	brightfield	GF82	3 images
P7	Horizontal	confocal	GF82	1 images
P7	Sagittal	brightfield	GF82	11 images
P7	Sagittal	confocal	GF82	12 images
E15.5	Horizontal	brightfield	GF82	3 images
E15.5	Horizontal	confocal	GF82	2 images
E15.5	Sagittal	brightfield	GF82	10 images
E15.5	Sagittal	confocal	GF82	1 images

BGEM Probe	Related ISH images
Crym	2881

Supporting literature:

PubMed ID
12702772

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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