Section Gene Symbol Age Orientation Objective Veracity Veracity Support T heat shock protein 8 Hspb8 E15.5 Horizontal 10X Confirmed Multiple Lines Match Matches In Situ Data

BX BAC Address marker BX1318 RP24-79A6 EGFP

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Add this image to your album Download this image at the scale shown below. Founder Line: HI62 See all MMRRC strains for : Hspb8 Get this mouse from MMRRC: STOCK Tg(Hspb8-EGFP)HI62Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX1318 UCSC Genome Browser for this BAC Address: RP24-79A6

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Comment on this Gene: No CNS expression literature found. The gene is reported to be present in senile plaques and amyloid angiopathy in Alzheimer_s disease. A mutation in the gene cause distal motor neuropathy. The BAC data is reproducible and grossly matches the in situ data from BGEM and Allen database. The BAC expresses in basal forebrain, which is confirmed by Allen in situ data. At E15-5, the BAC expresses in choroid plexus and ependymal cells lining the ventricles, but at lower levels.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Dorsal Horn	moderate to strong signal	region-specific
Ventral Horn	moderate to strong signal	region-specific

Other image sets for Hspb8

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	HI62	3 images
adult	Sagittal	brightfield	HI62	10 images
adult	Sagittal	confocal	HI62	1 images
adult	Sagittal	confocal	HI62	2 images
P7	Horizontal	brightfield	HI62	3 images
P7	Horizontal	confocal	HI62	1 images
P7	Sagittal	brightfield	HI62	11 images
P7	Sagittal	confocal	HI62	2 images
P7	Sagittal	confocal	HI62	5 images
E15.5	Horizontal	brightfield	HI62	3 images
E15.5	Horizontal	confocal	HI62	1 images
E15.5	Sagittal	brightfield	HI62	10 images
E15.5	Sagittal	confocal	HI62	4 images

BGEM Probe	Related ISH images
Hspb8	2976

Supporting literature:

PubMed ID
15122253
16485107
11470154

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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