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| Comment on this Gene: Many expression references. But almost all of them reported induced expression of Egr1 in various brain regions after certain stimuli, not endogenous Egr1 mRNA distribution. The mostly studied brain regions include caudate putamen, neocortex, forebrain and hippocampus. Three BAC lines are identical at P7. The BAC expresses in both neurons and glia. The overall expression pattern agrees with BGEM in situ data and the literature. |
| structure | Expression Level | Expression Pattern | Cell types | Subtypes |
|---|---|---|---|---|
| Cerebral cortex | moderate to strong signal | scattered | ||
| Piriform cortex | moderate to strong signal | region-specific and scattered | ||
| Entorhinal Cortex | moderate to strong signal | scattered | ||
| Hippocampus | moderate to strong signal | scattered | ||
| Caudate Putamen | moderate to strong signal | scattered | ||
| Amygdala | moderate to strong signal | region-specific and scattered | ||
| Cerebellum | moderate to strong signal | scattered |
| age | orientation | Acquisition technique | Founder Line | Batch |
|---|---|---|---|---|
| adult | Horizontal | brightfield | GO90 | 3 images |
| adult | Sagittal | brightfield | GO90 | 10 images |
| P7 | Horizontal | brightfield | GO90 | 3 images |
| P7 | Sagittal | brightfield | GO90 | 11 images |
| P7 | Sagittal | confocal | GO90 | 8 images |
| E15.5 | Horizontal | brightfield | GO90 | 3 images |
| E15.5 | Horizontal | confocal | GO90 | 1 images |
| E15.5 | Sagittal | brightfield | GO90 | 10 images |
| BGEM Probe | Related ISH images |
|---|---|
| Egr1 | 2360 |
| Veracity | definition |
|---|---|
| Confirmed | Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database. |
| To Be Confirmed | To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available. |
| Anomalous | Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects). |