Structure Gene Symbol Age Orientation Objective Veracity Veracity Support Substantia Nigra ectodermal-neural cortex 1 Enc1 adult Sagittal 40X Confirmed Multiple Lines Match Matches In Situ Data Supported by Literature

BX BAC Address marker BX994 RP23-158A14 EGFP

Other structures in this brain: CER CEX CPU MED OLF OLF2 SNR SNR2 VST

Add this image to your album Download this image at the scale shown below. Founder Line: FD162 See all MMRRC strains for : Enc1 Get this mouse from MMRRC: STOCK Tg(Enc1-EGFP)FD162Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX994 UCSC Genome Browser for this BAC Address: RP23-158A14

Read gene expression annotations for this image View other image sets for Enc1

Enc1 is expressed in neurons in the compact part of the substantia nigra. Glia are also labeled. Compare this confocal image with brightfield section 5.

Comment on this Gene: The BAC data is reproducible and consistent with both literature and BGEM in situ data. The EGFP reporter gene is expressed in both neurons and glia in BAC mice. It can not be determined the cell types in which Enc1 mRNA is expressed from the in situ data. The BAC data detects additional expression in cerebellum and brainstem.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Substantia Nigra	moderate to strong signal	region-specific and scattered	neuron glial cell

Other image sets for Enc1

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	FD162	3 images
adult	Horizontal	confocal	FD162	2 images
adult	Sagittal	brightfield	FD162	10 images
adult	Sagittal	confocal	FD162	9 images
P7	Horizontal	brightfield	FD162	3 images
P7	Horizontal	confocal	FD162	2 images
P7	Sagittal	brightfield	FD162	11 images
P7	Sagittal	confocal	FD162	8 images
E15.5	Horizontal	confocal	FD162	1 images
E15.5	Sagittal	brightfield	FD162	9 images
E15.5	Sagittal	confocal	FD162	3 images

BGEM Probe	Related ISH images
Enc1	411
Enc1	1321

Supporting literature:

PubMed ID
9096139

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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