Section Gene Symbol Age Orientation Objective Veracity Veracity Support 01 cyclin D1 Ccnd1 E15.5 Sagittal 10X Confirmed Matches In Situ Data Supported by Literature

BX BAC Address marker BX1033 RP23-294B14 EGFP

Other cross-sections of this brain: 01 02 03 04 05 06 07 08 09 10 (thumbnails not to scale)

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Add this image to your album Download this image at the scale shown below. Founder Line: FP70 See all MMRRC strains for : Ccnd1 Get this mouse from MMRRC: STOCK Tg(Ccnd1-EGFP)FP70Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX1033 UCSC Genome Browser for this BAC Address: RP23-294B14

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Comment on this Gene: No detailed CNS expression literature found. The postnatal BAC shows correct expression in cerebellum. The cerebellar IGL is relatively intensely stained in BAC mice due to the stability of EGFP protein. In addition to cerebellum, the EGFP reporter gene is expressed in many brain areas at P7, which are not found in the in situ data. However, these expression sites are reproducible in two different BAC targeting events. In E15-5 BAC data, postmitotic cells are mostly labeled instead of mitotic cells in VZs as shown by the in situ.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Cerebral cortex	moderate to strong signal	region-specific
Caudate Putamen	moderate to strong signal	region-specific
Amygdala	moderate to strong signal	region-specific

Other image sets for Ccnd1

age	orientation	Acquisition technique	Founder Line	Batch
P7	Horizontal	brightfield	FP70	3 images
P7	Horizontal	confocal	FP70	1 images
P7	Sagittal	brightfield	FP70	11 images
P7	Sagittal	confocal	FP70	7 images
E15.5	Horizontal	brightfield	FP70	3 images
E15.5	Horizontal	confocal	FP70	1 images
E15.5	Sagittal	brightfield	FP70	10 images
E15.5	Sagittal	confocal	FP70	6 images

BGEM Probe	Related ISH images
Ccnd1	48
Ccnd1	54

Supporting literature:

PubMed ID
7664341
12502747

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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