Section Gene Symbol Age Orientation Objective Veracity Veracity Support 06 protease, serine, 12 neurotrypsin (motopsin) Prss12 adult Sagittal 10X Confirmed Multiple Lines Match Matches In Situ Data Supported by Literature

BX BAC Address marker BX1010 RP23-36O5 EGFP

Other cross-sections of this brain: 01 02 03 04 05 06 07 08 09 10 (thumbnails not to scale)

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Add this image to your album Download this image at the scale shown below. Founder Line: FI61 See all MMRRC strains for : Prss12 Get this mouse from MMRRC: STOCK Tg(Prss12-EGFP)FI61Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX1010 UCSC Genome Browser for this BAC Address: RP23-36O5

Read gene expression annotations for this image View other image sets for Prss12

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Comment on this Gene: The BAC data is reproducible and consistent with the literature in general. However, there are a few discrepancies. 1. The cited papers report that Prss12 mRNA is expressed in hippocampus CA1 region. The BAC expresses in subiculum, which is supported by Allen in situ data. 2. reduced expression in cortex in adult BAC mice. 3.the claustrum is nicely stained in BAC mice, which is confirmed by Allen in situ data.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Cerebral cortex	moderate to strong signal	region-specific	neuron
Piriform cortex	moderate to strong signal	region-specific and scattered	neuron
Subicular cortex	moderate to strong signal	region-specific	neuron
Hippocampus	undetectable	ND
Caudate Putamen	undetectable	ND
Ventral striatum	undetectable	ND
Globus Pallidus	undetectable	ND
Basal Forebrain	undetectable	ND
Thalamus	undetectable	ND
Midbrain	undetectable	ND
Substantia Nigra	undetectable	ND
Pons	undetectable	ND
Medulla	undetectable	ND
Cerebellum	undetectable	ND

Other image sets for Prss12

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	FI61	3 images
adult	Sagittal	brightfield	FI61	10 images
adult	Sagittal	confocal	FI61	1 images
P7	Horizontal	brightfield	FI61	3 images
P7	Sagittal	brightfield	FI61	11 images
P7	Sagittal	confocal	FI61	3 images
E15.5	Horizontal	brightfield	FI61	3 images
E15.5	Sagittal	brightfield	FI61	10 images
E15.5	Sagittal	confocal	FI61	1 images

BGEM Probe	Related ISH images
Prss12	2880

Supporting literature:

PubMed ID
10095086
11640897
9245503

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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