Structure Gene Symbol Age Orientation Objective Veracity Veracity Support
Midbrain insulin-like growth factor 1 Igf1 P7 Sagittal 25X Confirmed
  • Multiple Lines Match
  • Matches In Situ Data
  • Supported by Literature
    		•
    BX BAC Address marker
    BX540 RP23-73H21 EGFP
    Other structures in this brain:GENSAT Brain Atlas, expression of gene Igf1 in mouse age P7, confocal image
    CER    		GENSAT Brain Atlas, expression of gene Igf1 in mouse age P7, confocal image
    CEX    		GENSAT Brain Atlas, expression of gene Igf1 in mouse age P7, confocal image
    COR    		GENSAT Brain Atlas, expression of gene Igf1 in mouse age P7, confocal image
    HIP    		GENSAT Brain Atlas, expression of gene Igf1 in mouse age P7, confocal image
    MID    		GENSAT Brain Atlas, expression of gene Igf1 in mouse age P7, confocal image
    OTH
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  • Founder Line: CO18
  • See all MMRRC strains for : Igf1
  • Get this mouse from MMRRC: STOCK Tg(Igf1-EGFP)CO18Gsat/Mmnc: Details, Order
  • Get this BAC Clone from CHORI: BX540
  • UCSC Genome Browser for this BAC Address: RP23-73H21
    		•
  • Read gene expression annotations for this image
  • View other image sets for Igf1
    • GENSAT Mouse Brain Atlas, expression of gene Igf1 in the Midbrain of P7 mouse.
    Comment on this Gene:
    The BAC data is in agreement with the literature and BGEM in situ data. The prominent expression sites are found in MOB, cerebellum, inferior olive and superior colliculus. The literature has no consensus on the Igf1 expression inside the cerebellum (Purkinje cells vs granule cells). The BAC data shows strong expression in Purkinje cells and weak expression in granule cells, which is consistent with BGEM data. The BGEM data also reveals high levels of Igf-1 mRNA inside the thalamus, whereas weak expression in the same area is seen in BAC mice.

    Gene Expression Annotations for this image
    structureExpression LevelExpression PatternCell typesSubtypes
    Midbrainmoderate to strong signalregion-specific and scattered
  • neuron


    • Other image sets for Igf1
    age orientation Acquisition technique Founder Line Batch
    adult Horizontal brightfield CO18 3 images
    adult Sagittal brightfield CO18 10 images
    adult Sagittal confocal CO18 1 images
    adult Sagittal confocal CO18 4 images
    adult Sagittal confocal CO18 1 images
    P7 Horizontal brightfield CO18 3 images
    P7 Horizontal confocal CO18 1 images
    P7 Sagittal brightfield CO18 11 images
    P7 Sagittal confocal CO18 1 images
    P7 Sagittal confocal CO18 6 images
    P7 Sagittal confocal CO18 2 images
    E15.5 Horizontal brightfield CO18 3 images
    E15.5 Horizontal confocal CO18 2 images
    E15.5 Sagittal brightfield CO18 10 images
    E15.5 Sagittal confocal CO18 1 images

    BGEM Probe Related ISH images
    Igf1 399

    Supporting literature:
    PubMed ID
    1879610
    9051257
    2177145
    1311816


    Veracity definition
    Confirmed Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
    To Be Confirmed To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
    Anomalous Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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