GENSAT Project at Rockefeller University, Mouse Brain Atlas, Image Navigator

Section	Gene	Symbol	Age	Orientation	Objective	Veracity	Veracity Support
06	neurogenic differentiation 1	Neurod1	P7	Sagittal	10X	Confirmed	Multiple Lines Match Supported by Literature

BX	BAC Address	marker
BX590	RP24-151C22	EGFP

Other cross-sections of this brain:

GENSAT Brain Atlas, expression of gene Neurod1 in mouse age P7, brightfield image

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Founder Line: CR99

See all MMRRC strains for : Neurod1

Get this mouse from MMRRC: STOCK Tg(Neurod1-EGFP)CR99Gsat/Mmucd: Details, Order

Get this BAC Clone from CHORI: BX590

UCSC Genome Browser for this BAC Address: RP24-151C22

Read gene expression annotations for this image

View other image sets for Neurod1

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Comment on this Gene:
Two BAC lines are very similar at P7. Our BAC data is in good agreement with the literature. At P7, highest levels of expression are seen in MOB (glomerular layer), dentate gyrus of the hippocampus and cerebellum (granule cells). Staining is also present in cortex, thalamus, amygdala, colliculi and spinal cord, which have been reported by some of the literature. In the adult BAC brain, levels of EGFP expression in cortex, hippocampus and MOB are greatly reduced. The strong expression remains in cerebellum.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Olfactory Bulb	moderate to strong signal	region-specific and scattered	neuron	fibers
Cerebral cortex	moderate to strong signal	region-specific and scattered	neuron	interneuron pyramidal cell
Hippocampus	moderate to strong signal	region-specific	neuron	granule neuron of hippocampus fibers
Caudate Putamen	moderate to strong signal	scattered		fibers
Ventral striatum	moderate to strong signal	scattered		fibers
Globus Pallidus	weak signal	scattered		fibers
Basal Forebrain	weak signal	scattered		fibers
Thalamus	moderate to strong signal	region-specific and scattered	neuron	fibers
Midbrain	moderate to strong signal	region-specific and scattered	neuron
Substantia Nigra	undetectable	ND
Pons	moderate to strong signal	region-specific and scattered	neuron	fibers
Medulla	moderate to strong signal	region-specific and scattered	neuron	fibers
Cerebellum	moderate to strong signal	region-specific	neuron	granule neuron of cerebellum
Olfactory nerve layer	moderate to strong signal	ND
Internal capsule	weak signal	ND
Stria terminalis	moderate to strong signal	ND
Fornix	moderate to strong signal	ND

Other image sets for Neurod1

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	CR99	3 images
adult	Sagittal	brightfield	CR99	10 images
adult	Sagittal	confocal	CR99	2 images
P7	Horizontal	brightfield	CR99	3 images
P7	Sagittal	brightfield	CR99	11 images
P7	Sagittal	confocal	CR99	4 images
P7	Sagittal	confocal	CR99	1 images
E15.5	Horizontal	brightfield	CR99	3 images
E15.5	Sagittal	brightfield	CR99	10 images
E15.5	Sagittal	confocal	CR99	10 images
E15.5	Sagittal	confocal	CR99	2 images

BGEM Probe	Related ISH images
Neurod1	1224

Supporting literature:

PubMed ID
9454850
10398678
10767080
9039799

Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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