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Cre mice grouped by gene. (20 Cre lines of which 16 have images.)

In collaboration with the Intramural Program of the National Institute of Mental Health (PI: Dr. Charles Gerfen), GENSAT offers fully characterized transgenic BAC-Cre recombinase driver lines that allow for cell-specific gene manipulations in the central nervous system of the mouse. The aim of this project is to provide the scientific community with Cre driver lines that will target selected neuronal or glial populations in the brain and spinal cord (also see PMID: 17855595).

Click on a thumbnail to see all images for a particular gene and founder line. Or visit the Cre Pipeline to see what else is in production.

Gene Symbol	Gene	Founder Line	Marker	Cre expression pattern	View	Order from MMRRC
Chat	choline acetyltransferase	GM24	Cre	matches adult gene expression (all cholinergic neurons) identical to GM60		STOCK Tg(Chat-cre)24Gsat: Details, Order
Chat	choline acetyltransferase	GM60	Cre	matches adult gene expression (all cholinergic neurons)		STOCK Tg(Chat-cre)60Gsat: Details, Order
Chat	choline acetyltransferase	GM53	Cre	Cre expression limited to motor neurons, minimal expression in forebrain structures		STOCK Tg(Chat-cre)53Gsat: Details, Order
Drd1a	dopamine receptor D1A	FK150	Cre	matches adult gene expression pattern, nearly identical to Drd1a line EY262		STOCK Tg(Drd1a-cre)150Gsat: Details, Order
Drd1a	dopamine receptor D1A	EY262	Cre	matches adult gene expression		STOCK Tg(Drd1a-cre)262Gsat: Details, Order
Drd1a	dopamine receptor D1A	EY242	Cre	Cre expression limited primarily to suprachiasmatic hypothalamic nucleus and a very small number of scattered striatal neurons	no images available	STOCK Tg(Drd1a-cre)242Gsat: Details, Order
Drd2	dopamine receptor 2	ER43	Cre	in subset of adult Drd2 expressing neurons (primarily striatopallidal neurons)		STOCK Tg(Drd2-cre)43Gsat: Register Interest
Drd2	dopamine receptor 2	ER44	Cre	matches adult gene expression		STOCK Tg(Drd2-cre)44Gsat: Details, Order
Etv1	ets variant gene 1	GM225	Cre	neocortex layer 5		NA
Ntsr1	neurotensin receptor 1	GN220	Cre	neocortex layer 6		STOCK Tg(Ntsr1-cre)220Gsat: Details, Order
Ntsr1	neurotensin receptor 1	GN209	Cre			NA
Pcp2	Purkinje cell protein 2 (L7)	GN137	Cre	matches adult gene expression (cerebellum purkinje cells)		STOCK Tg(Pcp2-cre)137Gsat: Register Interest
Pcp2	Purkinje cell protein 2 (L7)	GN135	Cre	matches adult gene expression (cerebellum purkinje cells) identical to GN137		STOCK Tg(Pcp2-cre)135Gsat: Details, Order
Slc6a2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	FV319	Cre	NA	no images available	STOCK Tg(Slc6a2-cre)319Gsat: Register Interest
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	ET33	Cre	matches adult gene expression (serotonin neurons and sparse numbers in cortex)		STOCK Tg(Slc6a4-cre)33Gsat: Details, Order
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	ET127	Cre	matches adult (serotonin neurons) and developmental (neocortex layer 6) gene expression		STOCK Tg(Slc6a4-cre)127Gsat: Details, Order
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	EZ8	Cre-ER (inducible)	NA	no images available	STOCK Tg(Slc6a4-cre/Esr1)8Gsat: Register Interest
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	EZ13	Cre-ER (inducible)	NA	no images available	STOCK Tg(Slc6a4-cre/Esr1)13Gsat: Details, Order
Th	tyrosine hydroxylase	FI12	Cre	matches adult and developmental gene expression		STOCK Tg(Th-cre)12Gsat: Details, Order
Th	tyrosine hydroxylase	FI172	Cre	matches adult and developmental gene expression, identical to line FI12		STOCK Tg(Th-cre)172Gsat: Details, Order

9 total genes of which 8 genes have images.