Section Gene Symbol Age Orientation Objective Veracity Veracity Support T signal-regulatory protein alpha Sirpa P7 Horizontal 10X Confirmed Multiple Lines Match Matches In Situ Data

BX BAC Address marker BX854 RP23-101N2 EGFP

Other cross-sections of this brain: C L T (thumbnails not to scale)

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This image is in your album. Download this image at the scale shown below. Founder Line: EK150 Get this BAC Clone from CHORI: BX854 UCSC Genome Browser for this BAC Address: RP23-101N2

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Comment on this Gene: Limited expression literature. According to the paper, Ptpns1 mRNA is detected in cerebellar granule cells and Golgi cells. The BAC data is reproducible in multiple lines, but does not match the literature in cerebellar expression. BGEM in situ data shows a similar expression pattern as our BAC data at P7. However, it can not be determined the cell types from the in situ data. The P7 BAC data shows less staining in the thalamus.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Dorsal Horn	moderate to strong signal	region-specific	neuron glial cell
Ventral Horn	moderate to strong signal	region-specific	neuron glial cell

Other image sets for Sirpa

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	EK150	3 images
adult	Sagittal	brightfield	EK150	10 images
adult	Sagittal	confocal	EK150	8 images
P7	Horizontal	brightfield	EK150	3 images
P7	Horizontal	confocal	EK150	1 images
P7	Sagittal	brightfield	EK150	11 images
P7	Sagittal	confocal	EK150	5 images
E15.5	Horizontal	brightfield	EK150	3 images
E15.5	Horizontal	confocal	EK150	1 images
E15.5	Sagittal	brightfield	EK150	10 images
E15.5	Sagittal	confocal	EK150	4 images

BGEM Probe	Related ISH images
Sirpa	472

Supporting literature:

PubMed ID
9348339

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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